Abstract:Background: Depressive symptoms and major depressive disorder (MDD) occur ≥ 3 times as common in coronary artery disease (CAD) patients as in the general community, which confers an adjusted relative risk of 2 to 4 for mortality. There are emerging data on how to manage depressed CAD patients with MDD. Several illnesses are treated with two medications from the beginning. In the case of major depression, the standard practice is to sequentially try one medication at a time, each attempt requiring a minimum of … Show more
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