Inadequate Therapy Behavior Is Associated to Disease Flares in Patients With Rheumatoid Arthritis Who Have Achieved Remission With Disease-Modifying Antirheumatic Drugs

Effect of medication adherence on disease activity among Japanese patients with rheumatoid arthritis

“…The present results indicate that medication adherence could serve as a predictor for sustained low RA disease activity. A similar result was obtained in a previous study, which focused RA patients with clinical remission [ 14 ]. Additionally, we observed that medication adherence was significantly associated with the sustained low activity in patients with shorter disease duration.…”

Effect of medication adherence on disease activity among Japanese patients with rheumatoid arthritis

“…The present results indicate that medication adherence could serve as a predictor for sustained low RA disease activity. A similar result was obtained in a previous study, which focused RA patients with clinical remission [ 14 ]. Additionally, we observed that medication adherence was significantly associated with the sustained low activity in patients with shorter disease duration.…”

Evaluation of Adherence to Drug Treatment in Patients with Rheumatoid Arthritis

“…In this study, the non-adherent patients were having more disease activity and worse radiological findings by MSUS. This was in agreement with Waimann et al who found that patients with better adherence showed less disease activity 27 and Contreras-Yanez et al who reported that therapy behavior of patients with RA with mild/no disease activity and disability was poor and translated into disease flares 5 .…”

“…Age is not consistently associated with medication non-adherence. While some studies reported that older patients had better adherence, others documented that younger patients tends to be more adherers as we found 5,[17][18][19] . Multiple comorbidities and complex medical regimens, which are both often associated with an increased age, may be responsible for non-adherence 6 .…”

Predictors of health care drop-out in an inception cohort of patients with early onset rheumatoid arthritis

“…In addition, their compliance with treatment was prospectively assessed. Similar to previous published observations [ 6 – 16 ], poor compliance with therapy was frequent and was associated with worse physician- and patient-reported outcomes [ 5 , 17 , 18 ]. Moreover, when patients concomitantly identified a lack of financial resources and a lack of available medications at the drug store as reasons for nonadherence to therapy, they were at risk for recurrent abandonment of therapy and experienced even more unfavourable outcomes [ 19 ].…”

Effect of medication adherence on disease activity among Japanese patients with rheumatoid arthritis

“…The present results indicate that medication adherence could serve as a predictor for sustained low RA disease activity. A similar result was obtained in a previous study, which focused RA patients with clinical remission [ 14 ]. Additionally, we observed that medication adherence was significantly associated with the sustained low activity in patients with shorter disease duration.…”

Evaluation of Adherence to Drug Treatment in Patients with Rheumatoid Arthritis

“…In this study, the non-adherent patients were having more disease activity and worse radiological findings by MSUS. This was in agreement with Waimann et al who found that patients with better adherence showed less disease activity 27 and Contreras-Yanez et al who reported that therapy behavior of patients with RA with mild/no disease activity and disability was poor and translated into disease flares 5 .…”

“…Age is not consistently associated with medication non-adherence. While some studies reported that older patients had better adherence, others documented that younger patients tends to be more adherers as we found 5,[17][18][19] . Multiple comorbidities and complex medical regimens, which are both often associated with an increased age, may be responsible for non-adherence 6 .…”

Predictors of health care drop-out in an inception cohort of patients with early onset rheumatoid arthritis

“…In addition, their compliance with treatment was prospectively assessed. Similar to previous published observations [ 6 – 16 ], poor compliance with therapy was frequent and was associated with worse physician- and patient-reported outcomes [ 5 , 17 , 18 ]. Moreover, when patients concomitantly identified a lack of financial resources and a lack of available medications at the drug store as reasons for nonadherence to therapy, they were at risk for recurrent abandonment of therapy and experienced even more unfavourable outcomes [ 19 ].…”

Effect of medication adherence on disease activity among Japanese patients with rheumatoid arthritis

“…The present results indicate that medication adherence could serve as a predictor for sustained low RA disease activity. A similar result was obtained in a previous study, which focused RA patients with clinical remission [ 14 ]. Additionally, we observed that medication adherence was significantly associated with the sustained low activity in patients with shorter disease duration.…”

Evaluation of Adherence to Drug Treatment in Patients with Rheumatoid Arthritis

“…In this study, the non-adherent patients were having more disease activity and worse radiological findings by MSUS. This was in agreement with Waimann et al who found that patients with better adherence showed less disease activity 27 and Contreras-Yanez et al who reported that therapy behavior of patients with RA with mild/no disease activity and disability was poor and translated into disease flares 5 .…”

“…Age is not consistently associated with medication non-adherence. While some studies reported that older patients had better adherence, others documented that younger patients tends to be more adherers as we found 5,[17][18][19] . Multiple comorbidities and complex medical regimens, which are both often associated with an increased age, may be responsible for non-adherence 6 .…”

Predictors of health care drop-out in an inception cohort of patients with early onset rheumatoid arthritis

“…In addition, their compliance with treatment was prospectively assessed. Similar to previous published observations [ 6 – 16 ], poor compliance with therapy was frequent and was associated with worse physician- and patient-reported outcomes [ 5 , 17 , 18 ]. Moreover, when patients concomitantly identified a lack of financial resources and a lack of available medications at the drug store as reasons for nonadherence to therapy, they were at risk for recurrent abandonment of therapy and experienced even more unfavourable outcomes [ 19 ].…”