Normalization of urinary porphyrin level and disappearance of skin lesions after successful interferon therapy in a case of chronic hepatitis C complicated with porphyria cutanea tarda

Hepatitis C virus and lichen planus

“…An accumulation of cases and long‐term follow up are needed for elucidation of the therapeutic effects of IFN therapy on extrahepatic lesions. The therapeutic effects of IFN on porphyria cutanea tarda have also been reported in several reports in rapid succession 123–126 …”

Hepatitis C virus and lichen planus

“…An accumulation of cases and long‐term follow up are needed for elucidation of the therapeutic effects of IFN therapy on extrahepatic lesions. The therapeutic effects of IFN on porphyria cutanea tarda have also been reported in several reports in rapid succession 123–126 …”

Ineffective interferon treatment of chronic hepatitis C-associated porphyria cutanea tarda, but with a transient decrease in HCV RNA levels

“…It has been reported that IFN therapy improved levels of serum transaminases and urinary porphyrins and resolved the skin lesions, together with decreasing HCV RNA levels in patients with chronic hepatitis C-associated PCT. 18,19 The authors of these studies suggested that HCV infection was related to the pathogenesis of the PCT-associated liver injury. On the other hand, Sheikh et al 8 recently reported that IFN therapy improved serum transaminase and urinary porphyrin levels and resolved the skin lesions without producing any significant decrease in HCV RNA levels in a patient with chronic hepatitis Cassociated PCT.…”

Porphyria cutanea tarda, hepatitis C, and HFE gene mutations in north america†

“…French patients with PCT and HCV infection with non-type 1 genotypes have been described, 39 as has a Japanese man with PCT complicating chronic alcohol abuse and HCV infection caused by a genotype 2 strain. 52 In the latter patient, both the PCT and the HCV infection responded to interferon therapy. Thus, infection with HCV of genotype 1 is not a sine qua non for development of PCT complicating chronic hepatitis C.…”

Hepatitis C virus and lichen planus

“…An accumulation of cases and long‐term follow up are needed for elucidation of the therapeutic effects of IFN therapy on extrahepatic lesions. The therapeutic effects of IFN on porphyria cutanea tarda have also been reported in several reports in rapid succession 123–126 …”

Ineffective interferon treatment of chronic hepatitis C-associated porphyria cutanea tarda, but with a transient decrease in HCV RNA levels

“…It has been reported that IFN therapy improved levels of serum transaminases and urinary porphyrins and resolved the skin lesions, together with decreasing HCV RNA levels in patients with chronic hepatitis C-associated PCT. 18,19 The authors of these studies suggested that HCV infection was related to the pathogenesis of the PCT-associated liver injury. On the other hand, Sheikh et al 8 recently reported that IFN therapy improved serum transaminase and urinary porphyrin levels and resolved the skin lesions without producing any significant decrease in HCV RNA levels in a patient with chronic hepatitis Cassociated PCT.…”

Porphyria cutanea tarda, hepatitis C, and HFE gene mutations in north america†

“…French patients with PCT and HCV infection with non-type 1 genotypes have been described, 39 as has a Japanese man with PCT complicating chronic alcohol abuse and HCV infection caused by a genotype 2 strain. 52 In the latter patient, both the PCT and the HCV infection responded to interferon therapy. Thus, infection with HCV of genotype 1 is not a sine qua non for development of PCT complicating chronic hepatitis C.…”

Hepatitis C virus and lichen planus

“…An accumulation of cases and long‐term follow up are needed for elucidation of the therapeutic effects of IFN therapy on extrahepatic lesions. The therapeutic effects of IFN on porphyria cutanea tarda have also been reported in several reports in rapid succession 123–126 …”

Ineffective interferon treatment of chronic hepatitis C-associated porphyria cutanea tarda, but with a transient decrease in HCV RNA levels

“…It has been reported that IFN therapy improved levels of serum transaminases and urinary porphyrins and resolved the skin lesions, together with decreasing HCV RNA levels in patients with chronic hepatitis C-associated PCT. 18,19 The authors of these studies suggested that HCV infection was related to the pathogenesis of the PCT-associated liver injury. On the other hand, Sheikh et al 8 recently reported that IFN therapy improved serum transaminase and urinary porphyrin levels and resolved the skin lesions without producing any significant decrease in HCV RNA levels in a patient with chronic hepatitis Cassociated PCT.…”

Porphyria cutanea tarda, hepatitis C, and HFE gene mutations in north america†

“…French patients with PCT and HCV infection with non-type 1 genotypes have been described, 39 as has a Japanese man with PCT complicating chronic alcohol abuse and HCV infection caused by a genotype 2 strain. 52 In the latter patient, both the PCT and the HCV infection responded to interferon therapy. Thus, infection with HCV of genotype 1 is not a sine qua non for development of PCT complicating chronic hepatitis C.…”