2012
DOI: 10.1177/039463201202500209 View full text |Buy / Rent full text
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Abstract: Orally administered immunomodulatory drugs have recently demonstrated the ability to induce an oral tolerance via inhibition of effector T cells and induction of certain subsets of regulatory T cells (Tregs) which have the potential to prevent several autoimmune diseases. In the present study, we hypothesized that short-term, low-dose, oral FTY720 administration may induce latency-associated peptide (LAP) Tregs and CD4+ Foxp3+ Tregs in atherogenesis, potentially resulting in remission of early development of a… Show more

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