A Nanoporous Graphene/Nitrocellulose Membrane Beneficial to Wound Healing

Abstract

Adequate treatment of skin wounds is vital to health. Nitrocellulose bandage as a traditional wound dressing is widely used for wound healing, but its limited air permeability and poor sterilization need to be improved for enhancing the actual efficacy. Here, nanoporous graphene (NPG) is used to mix into nitrocellulose for preparing a composite membrane, which exhibits a moderate transmission rate of water vapor, excellent toughness performance, and good biocompatibility. Moreover, the membrane shows an excellent broadspectrum antibacterial property (>98%, Escherichia coli; >90%, Staphylococcus aureus) and can reduce the risk of microbial infection for the body after trauma. Importantly, after using the nanoporous graphene/ nitrocellulose membrane, the wound closure percentage reaches 93.03 ± 1.08% at 7 days after the trauma, and the degree of skin tissue recovery is also improved significantly. Therefore, this study develops a highly efficient wound healing dressing, which is expected to be used directly in clinics.

Green- and Red-Emitting Fluorescent Silicon Nanoparticles: Synthesis, Mechanism, and Acid Phosphatase Sensing

“…O 1s, O–Si (531.4 eV), O–Si (532.0 eV), O–C (532.7 eV). Si 2p, Si–C (101.6 eV), Si–N (102.1 eV), Si–O (102.7 eV). ,− For the R-SiNPs, the high-resolution full and fine spectra of C 1s, N 1s, O 1s and Si 2p were basically consistent with the results of the G-SiNPs (Figures S5b and e–h). Importantly, the XPS analysis results were identified with the FTIR characterization data, which further illustrated that the structures of the above two SiNPs contained −OH, −NH 2 and Si–N bonds.…”

In situ forming double-crosslinked hydrogels with highly dispersed short fibers for the treatment of irregular wounds

“…[1][2][3] It has been well established that a favorable microenvironment plays a significant role in wound healing and tissue remodeling. 4,5 At present, various wound dressings have been developed to expedite the repair of skin wounds, including functional gauze, 6 membranes, 7 sponges, 8 hydrocolloids, 9 polymersomes, 10 and hydrogels. 11 Among them, hydrogel dressings have become increasingly popular due to oxygen permeability, wound exudate absorption property, and moisture retention characteristics.…”

Functionalization of Nitrocellulose Film by AB-Type Click Polymerization: Methods and Property Enhancements

“…It has a glucopyranose repeating unit containing varied numbers of nitro groups and is classified based on the degree of nitration on cellulose units. , Usability and areas of application depend on the degree of nitration and nitrogen contents . Nitrocellulose with nitrogen content >12.5% is used as a major component of propellants for fireworks, rockets, guns, etc. , On the contrary, NC with nitrogen content <12.5% can be used in coatings, microelectronics, lacquers, inks, purifying membrane, adhesives, wound dressing applications, etc. ,− For example, the nitrocellulose membranes with a lower percentage of nitrogen has been used as a strip for diagnosis tests , and wound healing material . For other applications, Mujawar et al fabricated nitrocellulose membrane pads in cameras and confocal laser scanning microscopes, where the transparency of the material is a key factor.…”

“…2,12−14 For example, the nitrocellulose membranes with a lower percentage of nitrogen has been used as a strip for diagnosis tests 15,16 and wound healing material. 17 For other applications, Mujawar et al fabricated nitrocellulose membrane pads in cameras and confocal laser scanning microscopes, 18 where the transparency of the material is a key factor. Along the same line, Zhang et al investigated the usability of nitrocellulose membranes for imaging application by Raman-scattering methods.…”