Establishing computed tomography–defined visceral fat area thresholds for use in obesity-related cancer research

Beyond central adiposity: Liver fat and visceral fat area are associated with metabolic syndrome in morbidly obese patients

“…As such waist circumference, being easier to determine, has been adopted as the risk marker for metabolic disease [8]. However, due to the limitations expressed above, the classification of morbidly obese patients with waist circumference does not correlate with metabolic risk.…”

Influence of body composition profile on outcomes following colorectal cancer surgery

“…Reduced L3 skeletal muscle index (myopenia) and low MA (myosteatosis) were identified using predefined sex-specific skeletal muscle index cut-off points. Increased VAT area (visceral obesity) was also described by using sex-specific and pathologically relevant cut-off values 9,10 . Myopenic obesity was defined as the combination of myopenia with a BMI of over 30 kg/m 2 .…”

“…Skeletal muscle and visceral adipose tissue (VAT) areas at the lumbar vertebral landmark (L3) have been shown to correspond to whole-body tissue quantities in non-malignant populations as well as in patients with cancer. Visceral obesity, defined as the excess accumulation of intra-abdominal adipose tissue, and myopenia are both occult conditions that can be identified by CTBC analysis 9,10 . It is also feasible using Hounsfield unit (HU) disparity in skeletal muscle tissue to determine intramyocellular lipid accumulation, termed myosteatosis, which is related to pain, functional decline, obesity and insulin resistance 11,12 .…”

The role of body composition evaluation by computerized tomography in determining colorectal cancer treatment outcomes: A systematic review

“…4 Sarcopenia, originally described as the depletion of skeletal muscle with age, has also been identified as a predictor of poor outcome in gastrointestinal cancers. 5,6 A number of methods for BC measurement have been proposed including assessments at the atomic, molecular, cellular, tissue-system and whole-body levels. 7 Techniques used include bioelectrical impedance analysis, dilution techniques, air displacement plethysmography, and image based approaches such as dual energy X-ray, magnetic resonance imaging, and computer tomography (CT).…”