Hemispheric Asymmetry in the Expression of Positive and Negative Emotions

Sackeïm, Harold A.; Greenberg, Mark S.; Weiman, Andrew L.; Gur, Ruben C.; Hungerbühler, Jean Pierre; Geschwind, Norman

doi:10.1001/archneur.1982.00510160016003

Cited by 622 publications

(227 citation statements)

References 69 publications

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“…We matched our image sets on luminance, and used black and white images, thus making it unlikely that color composition could affect these results. The direct comparison of pleasant with aversive stimuli revealed an activation focus in the left frontal pole (Figure 3), consistent with the lateralization of valence hypothesis (Davidson, 1995;Natale et al, 1983;Sackeim et al, 1982). However, the region of interest analysis revealed that activities to pleasant, neutral, and blank stimuli were nearly identical, whereas activity decreased in response to aversive stimuli.…”

Section: Neuropsychopharmacologysupporting

confidence: 80%

Extended Amygdala and Emotional Salience: A PET Activation Study of Positive and Negative Affect

Liberzon

Phan

Decker³

et al. 2002

Neuropsychopharmacol

163

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Functional neuroimaging studies have implicated amygdaloid and basal forebrain regions, including sublenticular extended amygdala (SLEA), in the mediation of aversive emotional responses. However, it is not clear whether SLEA responds to 'aversiveness' or to general stimulus salience. We predicted that both pleasant and aversive stimuli would activate this region. Using [15 O] water PET, we studied 10 healthy subjects while viewing pleasant, aversive, neutral, and blank images. Each subject underwent eight scans, which were processed and averaged with standard statistical methods. Both positive and negative stimuli activated regions in SLEA. Both positive and negative content activated the visual cortex, relative to neutral content. Aversive stimuli deactivated the left frontal pole, relative to positive and neutral stimuli. These findings demonstrate that both positive and negative emotional content evokes processing in the sublenticular/ extended amygdala region, suggesting that this region is involved in general emotional processing, such as detection or attribution of salience.

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Section: Neuropsychopharmacologysupporting

confidence: 80%

Extended Amygdala and Emotional Salience: A PET Activation Study of Positive and Negative Affect

Liberzon

Phan

Decker³

et al. 2002

Neuropsychopharmacol

163

View full text Add to dashboard Cite

show abstract

“…[41][42][43][44] The balance between the right and left hemispheres is very important to adaptive emotion regulation, and hemispheric asymmetry has been observed in normal affective processing of positive and negative emotions. 45,46 Previous studies have indicated that the left PFC activates more during the regulation of negative affect 47 and approach-related positive affect. 48 Studies involving depressed individuals have shown decreased activation in the left PFC and increased activation in the right PFC in response to sad mood induction.…”

Section: Discussionmentioning

confidence: 99%

Functional connectivity between the amygdala and prefrontal cortex in medication-naive individuals with major depressive disorder

Kong

Chen

Tang

et al. 2013

J Psychiatry Neurosci

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“…The communicative processes, in turn, should be further divided into perceptual and expressive components, and into various communicative channels such as lexical, prosodic, or facial expression (Borod 1993;Borod et al 1998). Taking all these aspects into account, a trend can be observed in the literature: the perception of emotions from facial expressions appears to be consistently lateralized, regardless of valence, toward the RH (Borod 1992;Bryden 1982;Sackeim et al 1982). Conversely, the valence hypothesis seems to apply to the behavioural expression and/or experience of emotion (Canli 1999;Davidson 1995).…”

Section: Discussionmentioning

confidence: 99%

Functional asymmetry and interhemispheric cooperation in the perception of emotions from facial expressions

et al. 2005

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The present study used the redundant target paradigm on healthy subjects to investigate functional hemispheric asymmetries and interhemispheric cooperation in the perception of emotions from faces. In Experiment 1 participants responded to checkerboards presented either unilaterally to the left (LVF) or right visual half field (RVF), or simultaneously to both hemifields (BVF), while performing a pointing task for the control of eye movements. As previously reported (Miniussi et al. in J Cogn Neurosci 10:216-230, 1998), redundant stimulation led to shorter latencies for stimulus detection (bilateral gain or redundant target effect, RTE) that exceeded the limit for a probabilistic interpretation, thereby validating the pointing procedure and supporting interhemispheric cooperation. In Experiment 2 the same pointing procedure was used in a go/no-go task requiring subjects to respond when seeing a target emotional expression (happy or fearful, counterbalanced between blocks). Faster reaction times to unilateral LVF than RVF emotions, regardless of valence, indicate that the perception of positive and negative emotional faces is lateralized toward the right hemisphere. Simultaneous presentation of two congruent emotional faces, either happy or fearful, produced an RTE that cannot be explained by probability summation and suggests interhemispheric cooperation and neural summation. No such effect was present with BVF incongruent facial expressions. In Experiment 3 we studied whether the RTE for emotional faces depends on the physical identity between BVF stimuli, and we set a second BVF congruent condition in which there was only emotional but not physical or gender identity between stimuli (i.e. two different faces expressing the same emotion). The RTE and interhemispheric cooperation were present also in this second BVF congruent condition. This shows that emotional congruency is the sufficient condition for the RTE to take place in the intact brain and that the cerebral hemispheres can interact in spite of physical differences between stimuli.

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Hemispheric Asymmetry in the Expression of Positive and Negative Emotions

Cited by 622 publications

References 69 publications

Extended Amygdala and Emotional Salience: A PET Activation Study of Positive and Negative Affect

Extended Amygdala and Emotional Salience: A PET Activation Study of Positive and Negative Affect

Functional connectivity between the amygdala and prefrontal cortex in medication-naive individuals with major depressive disorder

Functional asymmetry and interhemispheric cooperation in the perception of emotions from facial expressions

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