Mindfulness‐Based Stress Reduction and Mindfulness‐Based Cognitive Therapy – a systematic review of randomized controlled trials

Fjorback, Lone Overby; Arendt, Mikkel; Ørnbøl, Eva; Fink, Per; Walach, Harald

doi:10.1111/j.1600-0447.2011.01704.x

Cited by 678 publications

(450 citation statements)

References 42 publications

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“…It is based on the Mindfulness-based Stress Reduction (MBSR) program (12) and is combined with cognitive therapy techniques including psycho-education on depression and relapse prevention strategies. MBCT has been found to be effective in preventing relapse to depression in MDD for those with three or more past episodes (13)(14)(15)(16), in reducing current depressive symptoms (17,18) and lowering comorbid anxiety (19).…”

Section: Introductionmentioning

confidence: 99%

A randomized controlled trial of mindfulness‐based cognitive therapy for bipolar disorder

Perich

Manicavasagar

Mitchell

et al. 2012

Acta Psychiatr Scand

111

118

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A randomized controlled trial of mindfulness-based cognitive therapy for bipolar disorder.Objective: To compare the efficacy of mindfulness-based cognitive therapy (MBCT) plus treatment as usual (TAU) to TAU alone for patients with bipolar disorder over a 12-month follow-up period. Method: Participants with a DSM-IV diagnosis of bipolar disorder were randomly allocated to either MBCT plus TAU or TAU alone. Primary outcome measures were time to recurrence of a DSM-IV major depressive, hypomanic or manic episode; the Montgomery-Å sberg Depression Rating Scale (MADRS); and Young Mania Rating Scale (YMRS). Secondary outcome measures were number of recurrences, the Depression Anxiety Stress Scales (DASS), and the State Trait Anxiety Inventory (STAI). Results: Ninety-five participants with bipolar disorder were recruited to the study (MBCT = 48; TAU = 47). Intention-to-treat (ITT) analysis found no significant differences between the groups on either time to first recurrence of a mood episode or total number of recurrences over the 12-month period. Furthermore, there were no significant betweengroup differences on the MADRS or YMRS scales. A significant between-group difference was found in STAI -state anxiety scores. There was a significant treatment by time interaction for the DASachievement subscale. Conclusion: While MBCT did not lead to significant reductions in time to depressive or hypo/manic relapse, total number of episodes, or mood symptom severity at 12-month follow-up, there was some evidence for an effect on anxiety symptoms. This finding suggests a potential role of MBCT in reducing anxiety comorbid with bipolar disorder. Significant outcomes T. Perich• Mindfulness-based cognitive therapy (MBCT) significantly improved state anxiety for those diagnosed with bipolar disorder over a 12-month follow-up period.• Improvements were found in reducing dysfunctional attitudes surrounding ideas of achievement for those allocated to MBCT. Limitations• The small sample size and high drop-out rate over the 12-month follow-up period.• A shorter follow-up period than other published trials of MBCT. 333

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Section: Introductionmentioning

confidence: 99%

A randomized controlled trial of mindfulness‐based cognitive therapy for bipolar disorder

Perich

Manicavasagar

Mitchell

et al. 2012

Acta Psychiatr Scand

111

118

View full text Add to dashboard Cite

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“…[14][15][16][17] It can result in unique skills for chronic pain management, such as acceptance, complementing those acquired through CBT, a part of ''usual care'' for chronic pain, [18][19][20][21][22] and potentially enhancing its benefits. [21][22][23][24][25][26] MM is perceived as safe and effective for pain reduction and has established empirical support for reducing symptoms of anxiety, depression, and stress-all problems commonly co-occurring with and affecting outcomes in chronic pain. 27,28 Research has indicated that MM practice can influence function of the brain areas associated with pain, attention, and emotional response, implicating them as potential mechanisms of action.…”

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confidence: 99%

Mindfulness Meditation-Based Intervention Is Feasible, Acceptable, and Safe for Chronic Low Back Pain Requiring Long-Term Daily Opioid Therapy

Zgierska

Burzinski

Cox

et al. 2016

The Journal of Alternative and Complementary Medicine

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Objective: Although mindfulness meditation (MM) is increasingly used for chronic pain treatment, limited evidence supports its clinical application for opioid-treated chronic low back pain (CLBP). The goal of this study was to determine feasibility, acceptability, and safety of an MM-based intervention in patients with CLBP requiring daily opioid therapy. Design: 26-week pilot randomized controlled trial comparing MM-based intervention, combined with usual care, to usual care alone. Setting: Outpatient. Patients: Adults with CLBP treated with ‡30 mg of morphine-equivalent dose (MED) per day for 3 months or longer. Interventions: Targeted MM-based intervention consisted of eight weekly 2-hour group sessions and home practice (30 minutes/d, 6 days/wk) during the study. ''Usual care'' for opioid-treated CLBP was provided to participants by their regular clinicians. Outcome measures: Feasibility and acceptability of the MM intervention were assessed by adherence to intervention protocol and treatment satisfaction among experimental participants. Safety was evaluated by inquiry about side effects/adverse events and opioid dose among all study participants. Results: Thirty-five participants enrolled during the 10-week recruitment period. The mean age (-standard deviation) was 51.8 -9.7 years; the patients were predominantly female, with substantial CLBP-related pain and disability, and treated with 148.3 -129.2 mg of MED per day. All participants completed baseline assessments; none missed both follow-up assessments or withdrew. Among experimental participants (n = 21), 19 attended 1 or more intervention sessions and 14 attended 4 or more. They reported, on average, 164.0 -122.1 minutes of formal practice per week during the 26-week study and 103.5 -111.5 minutes of brief, informal practice per week. Seventeen patients evaluated the intervention, indicating satisfaction; their qualitative responses described the course as useful for pain management (n = 10) and for improving pain coping skills (n = 8). No serious adverse events or safety concerns occurred among the study participants. Conclusions: MM-based intervention is feasible, acceptable, and safe in opioid-treated CLBP.

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“…Mindfulness-based interventions have shown promising therapeutic outcomes for several psychological and physical disorders, such as chronic pain, depression, postpartum depression, anxiety, and addictions (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20). This intervention aims at alleviating pathogenic agents, while also emphasizing on the capacities of mindfulness-based interventions to optimize psychological and behavioral functioning.…”

Section: Introductionmentioning

confidence: 99%

Well-Being, Mental Health, General Health and Quality of Life Improvement Through Mindfulness-Based Interventions: A Systematic Review and Meta-Analysis

Aghaie

Roshan

Mohamadkhani

et al. 2018

Iran Red Crescent Med J

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Context: Mindfulness-based interventions have shown promising therapeutic outcomes in improving well-being, mental health, general health, and quality of life, however, findings in this regard are inconsistent. The present study aimed at clarifying this inconsistency in the literature focusing on the Iranian studies through a systematic review and meta-analysis study. Evidence Acquisition: The databases of Pubmed, Scopus, Doaj, EBSCO, Iranmedex, MagIran, SID, and Comprehensive Human Sciences Portal, and additional resources were searched using the set terms of "mindfulness" OR "mindfulness-based cognitive therapy" OR "MBCT" OR "mindfulness-based stress reduction" OR "MBSR" AND "intervention" AND "well-being" OR "health" OR "quality of life" and the time limit of the records was set between March 2008 and May 2017. The language of search was restricted to English and Farsi. Only studies conducted on Iranian populations were selected in this study. Thirty-five studies conducted on 3013 subjects were assessed. Cochrane Q-test and I-squared index were used to detect the heterogeneity among results, and fixed effect model with a 95% Confidence Interval (CI) was applied. The effect size of mindfulness-based interventions on well-being, mental health, general health, and quality of life improvement, measured by Hedge's g ratios, were respectively 1.54, 1.08, 0.89, and 1.87. Results: The findings showed that the effect size of mindfulness-based interventions on well-being, mental health, general health, and quality of life improvement were of high magnitude, according to the Cohen's table. Conclusion: Mindfulness-based interventions effectively improved well-being, health, and quality of life.

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Mindfulness‐Based Stress Reduction and Mindfulness‐Based Cognitive Therapy – a systematic review of randomized controlled trials

Cited by 678 publications

References 42 publications

A randomized controlled trial of mindfulness‐based cognitive therapy for bipolar disorder

A randomized controlled trial of mindfulness‐based cognitive therapy for bipolar disorder

Mindfulness Meditation-Based Intervention Is Feasible, Acceptable, and Safe for Chronic Low Back Pain Requiring Long-Term Daily Opioid Therapy

Well-Being, Mental Health, General Health and Quality of Life Improvement Through Mindfulness-Based Interventions: A Systematic Review and Meta-Analysis

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