Plasma glucose levels and diabetes are independent predictors for mortality and morbidity in patients with SARS

Yang, Jin‐Kui; Feng, Yun‐Zhi; Yuan, Min; Yuan, Shan; Fu, Hang; Wu, Bing; Sun, Guangping; Yang, Guang; Zhang, X. L.; Wang, L.; Xu, Xiaojun; Chan, Juliana C.N.

doi:10.1111/j.1464-5491.2006.01861.x

Cited by 690 publications

(649 citation statements)

References 13 publications

Supporting

Mentioning

568

Contrasting

Unclassified

Order By: Relevance

“…For severe acute respiratory syndrome, which affected thousands of people in 2003, diabetes and poor glycaemic control were strongly associated with mortality (odds ratio 3·0; 95% CI 1·4-6·3). 107 In recent outbreaks of Middle East respiratory syndrome in Saudi Arabia, also caused by a novel coronavirus, diabetes was detected in 68% of cases and 66% of deaths. 108 This association could be due to increased susceptibility to infection or to increased likelihood of severe disease leading to healthcare attendance.…”

Section: Viral Infectionsmentioning

confidence: 99%

The global diabetes epidemic: what does it mean for infectious diseases in tropical countries?

Crevel

Vijver

Moore

2017

The Lancet Diabetes & Endocrinology

127

102

View full text Add to dashboard Cite

Tropical countries are experiencing a substantial rise in type 2 diabetes, which is often undiagnosed or poorly controlled. Since diabetes is a risk factor for many infectious diseases, this increase probably adds to the large infectious disease burden in tropical countries. We reviewed the literature to investigate the interface between diabetes and infections in tropical countries, including the WHO-defined neglected tropical diseases. Although solid data are sparse, patients with diabetes living in tropical countries most likely face increased risks of common and health-care-associated infections, as well as infected foot ulcers, which often lead to amputation. There is strong evidence that diabetes increases the severity of some endemic infections such as tuberculosis, melioidosis, and dengue virus infection. Some HIV and antiparasitic drugs might induce diabetes, whereas helminth infections appear to afford some protection against future diabetes. But there are no or very scarce data for most tropical infections and for possible biological mechanisms underlying associations with diabetes. The rise in diabetes and other non-communicable diseases puts a heavy toll on health systems in tropical countries. On the other hand, complications common to both diabetes and some tropical infections might provide an opportunity for shared services-for example, for eye health (trachoma and onchocerciasis), ulcer care (leprosy), or renal support (schistosomiasis). More research about the interaction of diabetes and infections in tropical countries is needed, and the infectious disease burden in these countries is another reason to step up global efforts to improve prevention and care for diabetes.

show abstract

Section: Viral Infectionsmentioning

confidence: 99%

The global diabetes epidemic: what does it mean for infectious diseases in tropical countries?

Crevel

Vijver

Moore

2017

The Lancet Diabetes & Endocrinology

127

102

View full text Add to dashboard Cite

show abstract

“…Male sex and comorbid conditions (eg, diabetes, hyperglycemia independent of diabetes, chronic hepatitis) increase mortality. 30,54,69 Overall, patients with and without comorbid conditions have 46% and 10% mortality, respectively. 30 Advanced age, high admission neutrophil count, and initial elevated lactic dehydrogenase (LDH) are independent correlates of an adverse outcome.…”

Section: Clinical Presentationsmentioning

confidence: 99%

Severe Acute Respiratory Syndrome (SARS)

Cleri

Ricketti

Vernaleo

2010

Infectious Disease Clinics of North America

View full text Add to dashboard Cite

show abstract

“…By contrast, hyperglycemia was an independent risk factor for increased mortality in patients with severe acute respiratory syndrome whether they had diabetes or not. 24 Suboptimal glucose control is associated with a poor prognosis in critically ill patients, often in association with bacterial sepsis, 25 and important parallels may exist between sepsis and infl uenza A(H5N1). Our suggestive fi ndings here on a limited number of patients emphasize the need for further research.…”

Section: Pleural Effusionsmentioning

confidence: 99%

Clinical Course of Avian Influenza A(H5N1) in Patients at the Persahabatan Hospital, Jakarta, Indonesia, 2005–2008

Soepandi¹,

Burhan²,

Mangunnegoro³

et al. 2010

Chest

View full text Add to dashboard Cite

show abstract

Plasma glucose levels and diabetes are independent predictors for mortality and morbidity in patients with SARS

Abstract: A known history of diabetes and ambient hyperglycaemia were independent predictors for death and morbidity in SARS patients. Metabolic control may improve the prognosis of SARS patients.

Cited by 690 publications

References 13 publications

The global diabetes epidemic: what does it mean for infectious diseases in tropical countries?

The global diabetes epidemic: what does it mean for infectious diseases in tropical countries?

Severe Acute Respiratory Syndrome (SARS)

Clinical Course of Avian Influenza A(H5N1) in Patients at the Persahabatan Hospital, Jakarta, Indonesia, 2005–2008

Contact Info

Product

Resources

About