Workers’ psychological distress, depression, and burnout symptoms: associations with diurnal cortisol profiles

Adrenal fatigue does not exist: a systematic review

“…Mental arithmetic and public speech stressors also performedLennartsson [24]201556H/BDCSRD; exclusion w/ SEQDHEA-S; ACTH; ACTH and DHEA-S post-TSST (TSST stress test performed)↓DHEA-S, ↓post-TSST DHEA-S, Nl ACTH, Nl post-TSST ACTHTao [23]2015171H/BMaslachMSC, ACTH↑ACTH, ↑MSCJonsson [29]201551H/BSMBQMSC, MSTNl MSC, ↓MSTLennartsson [27]201556H/BDCSRD and SMBQMSC, MST, ACTH, ACTH post-TSST (TSST stress test performed)Nl MSC, Nl MST, Nl ACTH, Nl post-TSST ACTHSevere BO: lower ACTH, cortisol response to TSST vs controls, whereas low BO: higher ACTH, cortisol responses vs controlsSchmaling [26]201562HealthyADASAUC, SCR↓AUC, ↓SCR31 couples studied, one of which had chronic fatigue (but not CFS)Sveinsdottir [68]20151150Chronic LombalgiaCFQDAC, CAR, SCR, NSCNl DAC, Nl CAR, Nl NSC, Nl SCR**Colocar como SAUDÁVEL – porque é só lombalgia (increased CAR in Low back pain)Powell [67]201576Multiple SclerosisCFQDAC, CAR, SCR↓DAC, ↑CAR, Nl SCRSleep disorders excluded; adjusted for depressive symptoms; NSC not published. Multiple sclerosis had increased awakening cortisol and decreased CARCruz [70]201543Breast cancerBFI and CFQMSC, DHEA-SNl MSC, Nl DHEA-SPts undergoing ChTx included anthracyclinesMarchand [31]20141043H/BMaslachDAC, CAR, SCR, NSC↑DAC, ↓CAR, ↑SCR, ↓NSCOnly BO; Groups of severe distress or depression not includedAggarwal [30]2014227HealthyCFQMSC, NSC, 0.25 mg DST, DHEA-SNl MSC, Nl NSC, Nl 0.25 mg DST, ↓DHEA-SEvaluation of chronic, widespread pain, chronic orofacial pain, chronic fatigue (but not CFS), irritable bowel syndromeTell D [71]2014130Breast cancerMFIDAC, CAR, SCR,...…”

Association between burnout and cortisol secretion, perceived stress, and psychopathology in palliative care unit health professionals

“…According to Heim et al (2000), the initial hyperactivity of the HPA axis can turn into hypoactivity after a period of chronic stress (Sonnentag, 2006). The possible link between dysregulated cortisol profiles and manifestations of burnout has also been suggested in other research (Marchand et al, 2014a). These findings provide further evidence of HPA axis deregulation when nurses exhibit high levels of burnout in all dimensions.…”

“…Chronic exposure to stressors can contribute to permanent HPA axis activation (Grossi et al, 2005;O'Connor et al, 2000). A typical diurnal cortisol rhythm shows a marked increase during the first hour after waking up, followed by a gradual reduction throughout the day, with levels at their lowest before bedtime (Marchand et al, 2014a;Pruessner et al, 1999). A typical diurnal cortisol rhythm shows a marked increase during the first hour after waking up, followed by a gradual reduction throughout the day, with levels at their lowest before bedtime (Marchand et al, 2014a;Pruessner et al, 1999).…”

Job burnout is associated with dysfunctions in brain mechanisms of voluntary and involuntary attention

“…Disturbed sleep, physical fatigue, and cognitive weariness are typical of job burnout (Ekstedt et al, 2006;Melamed et al, 1999). The symptoms overlap considerably with depression and psychological distress, especially in the more severe forms of job burnout but there is an increasing body of evidence supporting the argument that burnout and depression are not identical concepts (Ahola, Hakanen, Perhoniemi, & Mutanen, 2014;Bakker et al, 2000;Brenninkmeyer, Van Yperen, & Buunk, 2001;Iacovides, Fountoulakis, Kaprinis, & Kaprinis, 2003;Marchand, Durand, Juster, & Lupien, 2014).…”